It is too early to tell how well humans will mount effective antibodies, writes Katherine J. Wu. She shares information on challenges to immune development, viral replication and antigenic drift. If nothing else, her article is a decent review of virology and the challenges of protection.
Source: Smithsonian, March 30, 2020. Link.
Complicating matters further is the biology of SARS-CoV-2 itself. Viruses aren’t technically alive: While they contain genetic instructions to make more of themselves, they lack the molecular tools to execute the steps, and must hijack living cells to complete the replication process for them.”