Tuberculosis has killed more people in the past 2000 years than any other disease, and it has sickened many more, writes Ann Gibbons. Archaeogenetic research helps identify which TB pathogens that have changed our DNA and made us more resilient. “Infectious diseases are the strongest evolutionary pressure humans have to face. . .” Source: Science, March 4, 2021. … [Read more...]
Lyme disease is getting skinked
Black-legged ticks in the southeast U.S. prefer to feed on lizards, particularly skinks. Skinks don’t transmit Lyme as easily as the white-footed mice in the northeast U.S. Jean Tsao, a disease ecologist, and her team found a clear divide in ticks’ preferred hosts and behavior south of Virginia, matching the pattern of both tick infections and Lyme disease. Source: Science, … [Read more...]
SARS-CoV-2 virus drift and shift raises concerns
For animal health pros born before 1990, antigenic drift and antigenic shift are not mere terms. Rather, they have been part of life experiences. Canine coronavirus, bovine viral diarrhea and equine herpes virus are among viruses our industry has chased with vaccines and vaccine updates. Rapid advancements in genotyping and mass spectrum technologies have been helpful as we … [Read more...]
How cats get their stripes
Animal health pros interested in genetic mechanisms will find this article interesting. Evidently, the same genes color wild and domestic cats. Researchers say this is an example of nature’s thriftiness. Source: Science, December 2, 2020. Link. Gregory Barsh and his colleagues have shown that a 70-year-old theory explaining patterns in nature holds true for fur color in … [Read more...]
Polyclonal antibodies being developed IN cows for Covid-19 virus
SAb Biotherapeutics of Sioux Falls, South Dakota, is pursuing an extension of previous research in genetically modifying dairy cows so that certain immune cells carry the DNA that allows people to make Covid-19 antibodies. Cows become giant bioreactor antibody factories. They have more blood engineered to synthesize human versions of the proteins and their blood can also … [Read more...]