Veterinarians rely on macrolides to treat livestock diseases such as bovine respiratory disease. University of Sakatechewan researchers discovered the gene can break the ring structure of the antibiotic through hydrolysis which destroys the antibiotic’s structure.
Inactivation is concerning because it reduces the effective amount of antibiotics that are being delivered during an infection.” – Tony Ruzzini, PhD
Source: Phys.org, February 23, 2023. Link.
INSIGHTS: Many of the antibiotics used for livestock come from two classes: macrolides and fluorquinolones. Familiar macrolide brands include Micotil®, Increxxa®, Zactran®, Draxxin®, Zuprevo®, Macrosyn®, Tulissin® and Tylan®.