Researchers at the University of California-Davis challenged the theory that purebred dogs are more prone to genetic disorders than mixed breed dogs. They studied 27,254 dogs with inherited disorders over a five-year period. The theory that purebred dogs are more susceptible to inherited diseases only holds true for 10 out of the 24 disorders studied.
Source: Dogs Naturally, October 7, 2016.
Some of the conclusions include:
- The prevalence of disorders among purebred and mixed-breed dogs varied with the condition. Some conditions (14) have a clear distinction between purebred and mixed-breed dogs and others (10) show no difference.
- The results gave insight into the ability of breeding practices to reduce prevalence of disease. Reliable genetic tests or screening at a young age could reduce some disorders in the dog population as a whole.
- The researchers also commented that some disorders may require breed registry intervention to reduce selection pressures that contribute to a certain disorder in a breed.
- “Recently derived breeds” or breeds from similar lineages were more susceptible to certain disorders that affect all closely related purebreds.
- Disorders with equal prevalence in purebreds or mixed breeds seemed to be more ancient mutations that are widely spread through the dog population.
Cm haugo says
I am curious as to which disorders are breed associated and which are less associated in this study.
Kirk Augustine says
The study referenced was embedded in the article … see study JAVMA abstract at this link: https://www.ncbi.nlm.nih.gov/pubmed/23683021