Tremendous interest exists to understand how to use regenerative therapies (orthobiologics) such as platelet-rich plasma and mesenchymal stem cells to treat tendon and ligament injuries in horses.
Some tendon and ligament injuries have a better chance of benefiting from orthobiologics than others. Roger Smith, MA, VetMB, PhD, DEO, FHEA, LAAssocECVDI, Dipl. ECVSMR, ECVS, FRCVS, presents indications for their use and how to choose between the two therapies. He reviews tissues he would consider treating with either PRP or MSCs.
Source: The Horse, December 21, 2021. Link. Smith added that both PRP and stems cells are used commonly for contained tendon and ligament lesions diagnosed via ultrasound.
Veterinarians should use <orthobiologics> with caution given their limited evidence of efficacy and as part of an appropriate rehabilitation strategy.” – Roger Smith, MA, VetMB, PhD, DEO, FHEA, LAAssocECVDI, Dipl. ECVSMR, ECVS, FRCVS