Instead of killing harmful bacteria, freeze-drying preserves bacteria in raw meats and organs. Contrary to many recommendations, freeze-dried raw treats should not be given to dogs alone or mixed with kibble, according to Lee Pickett, VMD.
Source: Arkansas Democrat Gazette via AVMA Animal Health SmartBrief, June 5, 2023. Link. Freeze-drying is one of the best ways to preserve bacteria because the technique helps bacteria remain viable and healthy for decades, freeze-dried raw food is just as risky as unprocessed raw food.