
When pet owners seek nonsedative alternatives to previsit medications like gabapentin, pregabalin, and trazodone, Casozepine may be considered as a short-term intervention when patients are prone to stress during veterinary visits, writes Christine D. Calder, DVM, DACVB. Administration for two days before an appointment can lower stress levels, she says.
Source: Clinician’s Brief, December 2024. Link. Casozepine, is a peptide derived from breast milk that exerts anxiolytic effects by acting on gamma-aminobutyric acid receptors in the CNS. Available in capsule and chew forms, research in cats has demonstrated casozepine can help manage stress in unfamiliar settings and during veterinary visits.
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